= Minutes OmicsConnect 2012_04_03 = [[TOC()]] Att: Rob, Joeri, Morris During this meeting the first prototype and experiences loading data were discussed. (source: molgenis_apps/build_omicsconnect.xml) This resulted in a long list of issues: == References == * Accession and accession version is confusing * Proposed solution: use OntologyTerm table (or similar) to manage all accessions centrally. * PrimaryCitation -> update label to use not id but something more meaningful (what exactly? pubmedid? nice would be 'Adamusiak et al (2011) Human Mutation) * Accession * Many items should have accessions / alternateIds + versions * Proposal: central Accession table analogous to OntologyTerm (we could actually used OntologyTerm????) == Panel == * Panel.name -> Panel.identifier * remove Panel.ontologyReference * Add user interface to add 'species' * We need to link Panel -> other Panel (as subform of Panel) to being able to assemble panels from other panels using some SelectionCriteria == Study organization == * link Contributions <-> Study is missing (as consequence all contributions are shown) * Need more types of contribution types/roles * multiple roles (author, design, grant holder) * multiple affiliations * Action: * StudyAnalysisMethod = "protocols during study" or "used protocols" * todo: remove OntologyReference * todo: create better protocol editor (mref is confusing) * Field 'name' should become 'identifier' (unique) * optionally data model can have human readible names * Citation.publicationStatus should be xref->OntologyTerm * Experiment.design should be xref->OntologyTerm * DataSet.protocolParameters * Discussion: proposal to remove and instead refer to the Protocol (that has parameters) == Protocols and Measurement == * Do we really need Measurement? Can we not just use ObservableFeature directly? * Measurement gets lost when adding to subform of Protocol * this is the mref issue mentioned above * Measurement should not have direct xref to study, because * Study uses Protocol (multiple studies may) * Protocol uses Measurement (so indirectly the link is there) * Protocol.features -> rename to Protocol.parameters as it is confusing * Protocol.circumstances -> unclear, remove (people can use parameters instead?) * Hotlink * Still unclear on how to generalize; for now just apply to Study * UsedMarkerset * remove link to Study (because already links to Experiment) * Discussion: lookup label is now (Study_name:Experiment_name) == GWAS specific == * Significances + Frequencies * Change superclass (these are NOT ProtocolApplication) * Discussion if we can remove and instead use DataSet * Are these part of a DataSet i.e. a particular kind of data set? * Changer marker to be xref (instead of text) * remove odds ration and attr risk * PhenotypeProperty (is confusing compared to Measurement) * Property = Measurement? * Method = Protocol * More discussion needed? Would be nice to merge PhenotypeProperty with Measurement. * Chromosome * remove xref to study * add 'autosomal' * add 'order number' * Marker * remove 'label' * add c.dna and pdna notation? * residues and alleleSequence are same thing (remove alleleSequence) * validationCode should be xref->OntologyTerm * remove 'added from source build' * should alleles be stored elsewhere (see Allele table)? * PermittedGenotypes * residue-info * what is 'locgroup' (chado heritance) * what is 'target' (confusing because we use it in other meaning) == Actions == * Joeri will add xQTL extensions to OmicsConnnect * Morris will add NGS (Genome of NL) extensions to OmicsConnect * Morris will process as far as he can todos from this meeting in the model * Rob will integrate citation lookup (of gwascentral curation tool) to OmicsConnect * Later: discuss contribution model with Mummy, in particular issue on how to deal with affiliations/roles * All: create / get example data!