Changes between Version 3 and Version 4 of xQTLUserReview


Ignore:
Timestamp:
2011-11-10T11:24:15+01:00 (13 years ago)
Author:
jvelde
Comment:

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  • xQTLUserReview

    v3 v4  
     1== Panacea xQTL review Wed 9 nov 2011 ==
     2* Data curation and annotation of the Panacea Database (joint effort)
     3* Host project analyses:
     4 * Phase 1: Just add the R scripts as files for basic provenance
     5 * Phase 2: Being able to rerun important scripts such as sample mislabeling and QTL x Env
     6 * Phase 3: Make it easy to add and run any R script that was used
     7* Data matrix:
     8 * Download or visualize with CytoScape
     9 * Need new view with more organization/hierarchy: group by experiment or annotation
     10 * Need to couple this hierarchy with the ability to quickly run scripts for visualization or statistics on a piece of the data
     11* Need 'supersearch' which produces reports on concepts (ie. everything related to a marker or individual)
     12 * This should include a special 'QTL finder' tool to quickly create reports on findings using a matrix and/or traits as inputs
     13* Focus on pathways:
     14 * Want to query pathway information for an organism from 1..N sources (GO, WormBase, KEGG.. ?)
     15 * Want to couple existing gene annotations to these pathways, semi-automatically (?)
     16 * Want to use this information to run analysis/visualizations on these batches of genes
     17 * Want to create pathway plots (biology!) with the gathered information (e.g. QTL profiles)
     18 * Want to create CytoScape graphs of e.g. correlation of the genes
     19 
     20
     21== EURATRANS xQTL review Wed 9 nov 2011 ==
     22* Integrate with genome browser (gBrowse, formats WGL and GFF)
     23* Need to save any filter as a URL
     24* Need to clarify how a tool like gBrowse can specify a 'range' in filter URL syntax and link it
     25* Also need the 'range' to work on matrices with locus data (e.g. markers) via URL
     26* Need to add scripts as visualizers of data: e.g. let them appear in a list of possible plot types in matrix
     27* Search box bugs: no '_name' searches possible
     28* Use real column names instead of labels eventually, this is still very confusing
     29* Need for advanced matrix views:
     30 * On similar rows & columns, create 'subheaders' with multivalue display
     31 * Alternatively, matrix merge operation to concatenate them
     32 * Want to have a report on a value that appears in multiple matrices
     33 * And/or reports with plots for e.g. a marker or probe with all related information from all sources
     34
    135== xQTL LL user workshop Fri 28 Oct 2011 general comments ==
    236* Need more download formats: STATA, SAS, CSV (not TSV)